Plakophilin 2 antibody (C-Term)

Catalog No. ABIN954172

Product Details anti-Plakophilin 2 Antibody

Target: Plakophilin 2 (PKP2)

Binding Specificity: AA 837-866, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plakophilin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Plakophilin-2 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 837-866 amino acids from the C-terminal region of Human Plakophilin-2 Genename: PKP2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Plakophilin 2

Target: Plakophilin 2 (PKP2)

Alternative Name: Plakophilin-2 (PKP2 Products)

Background: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.Synonyms: PKP2

Molecular Weight: 97415 Da

Gene ID: 5318

NCBI Accession: NP_004563

Pathways: Cell-Cell Junction Organization, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection