Phospholipase C beta 1 antibody (C-Term)

Catalog No. ABIN954182

The Rabbit Polyclonal anti-Phospholipase C beta 1 antibody is suitable to detect Phospholipase C beta 1 in samples from Human. It has been validated for WB, FACS and EIA.

Quick Overview for Phospholipase C beta 1 antibody (C-Term) (ABIN954182)

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C beta 1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-Phospholipase C beta 1 Antibody

Binding Specificity: AA 1155-1184, C-Term

Specificity: This antibody recognizes Human PLCB1 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 1155~1184 amino acids from the C-terminal region of human PLCB1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Phospholipase C beta 1

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Alternative Name: PLCB1

Background: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta-1, KIAA0581, PLC beta1, PLC-I, PLC-beta-1, Phosphoinositide phospholipase C-beta-1, Phospholipase C-I, Phospholipase C-beta-1

Molecular Weight: 138567 Da

Gene ID: 23236

NCBI Accession: NP_056007

Pathways: WNT Signaling, AMPK Signaling, Thyroid Hormone Synthesis, Inositol Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, G-protein mediated Events