PLOD3 antibody (N-Term)

Catalog No. ABIN954206

Product Details anti-PLOD3 Antibody

Target: PLOD3 (Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3))

Binding Specificity: AA 85-113, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLOD3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human PLOD3 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 85-113 amino acids from the N-terminal region of human PLOD3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PLOD3

Target: PLOD3 (Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3))

Alternative Name: PLOD3 (PLOD3 Products)

Background: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.Synonyms: 2-oxoglutarate 5-dioxygenase 3, Lysyl hydroxylase 3, Procollagen-lysine

Molecular Weight: 84785 Da

Gene ID: 8985

NCBI Accession: NP_001075