PMS1 antibody (C-Term)

Catalog No. ABIN954221

The Rabbit Polyclonal anti-PMS1 antibody is suitable to detect PMS1 in samples from Human. It has been validated for WB and EIA.

Quick Overview for PMS1 antibody (C-Term) (ABIN954221)

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMS1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PMS1 Antibody

Binding Specificity: AA 693-722, C-Term

Specificity: This antibody recognizes Human PMS1 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 693-722 amino acids from the C-terminal region of human PMS1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PMS1

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Alternative Name: PMS1

Background: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.Synonyms: DNA mismatch repair protein PMS1, PMS1 protein homolog 1, PMSL1

Molecular Weight: 105830 Da

Gene ID: 5378

NCBI Accession: NP_000525