POFUT2 antibody (Middle Region)

Catalog No. ABIN954233

Product Details anti-POFUT2 Antibody

Target: POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Binding Specificity: AA 235-265, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POFUT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human POFUT2 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 235-265 amino acids from the Central region of human POFUT2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for POFUT2

Target: POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Alternative Name: POFUT2 (POFUT2 Products)

Synonyms: C21orf80 antibody, FUT13 antibody, fc46a11 antibody, wu:fc46a11 antibody, zgc:194822 antibody, 2310011G23Rik antibody, AI256847 antibody, BC003494 antibody, protein O-fucosyltransferase 2 antibody, POFUT2 antibody, pofut2 antibody, Pofut2 antibody

Background: Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF, MIM 131530)-like repeats or thrombospondin (THBS, see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857].Synonyms: C21orf80, FUT13, GDP-fucose protein O-fucosyltransferase 2, KIAA0958, O-FucT-2, Peptide-O-fucosyltransferase 2

Molecular Weight: 49976 Da

Gene ID: 23275

NCBI Accession: NP_056042