CFP antibody (Middle Region)
Quick Overview for CFP antibody (Middle Region) (ABIN954312)
Target
See all CFP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 203-233, Middle Region
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Specificity
- This antibody reaccts to CFP.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 203~233 amino acids from the Central region of human CFP
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CFP (Complement Factor P (CFP))
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Alternative Name
- Properdin
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Background
- This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.Synonyms: CFP, Complement factor P, PFC
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Molecular Weight
- 51276 Da
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Gene ID
- 5199
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NCBI Accession
- NP_001138724
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Pathways
- Complement System
Target
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