PSTPIP1 antibody (N-Term)

Catalog No. ABIN954360

The Rabbit Polyclonal anti-PSTPIP1 antibody (ABIN954360) specifically detects PSTPIP1 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for PSTPIP1 antibody (N-Term) (ABIN954360)

Target: PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSTPIP1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PSTPIP1 Antibody

Binding Specificity: AA 88-118, N-Term

Specificity: This antibody recognizes Human PSTPIP1 / CD2BP1 (N-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 88-118 amino acids from the N-terminal region of Human PSTPIP1 / CD28P1 Genename: PSTPIP1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PSTPIP1

Target: PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))

Alternative Name: PSTPIP1 / CD2BP1

Background: The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.Synonyms: CD2 antigen-binding protein 1, CD2 cytoplasmic tail-binding protein, CD2-binding protein 1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PEST phosphatase-interacting protein 1, PSTPIP, Proline-serine-threonine phosphatase-interacting protein 1

Molecular Weight: 47591 Da

Gene ID: 9051

NCBI Accession: NP_003969