PTTG1IP antibody (Internal Region)
Quick Overview for PTTG1IP antibody (Internal Region) (ABIN954383)
Target
See all PTTG1IP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Internal Region
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Specificity
- This antibody detects endogenous levels of total PTTG protein.
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Cross-Reactivity (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- Immunoaffinity Chromatography
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Immunogen
- Synthetic peptide from Human PTTG. Epitope: Internal.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PTTG1IP (Pituitary Tumor-Transforming 1 Interacting Protein (PTTG1IP))
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Alternative Name
- PTTG1IP
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Background
- The encoded protein, which directly binds to pituitary tumor-transforming protein-1 (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1.Synonyms: C21orf1, C21orf3, PBF, PTTG-binding factor, Pituitary tumor-transforming gene 1 protein-interacting protein, Pituitary tumor-transforming gene protein-binding factor
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Gene ID
- 754
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NCBI Accession
- NP_004330
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Pathways
- Protein targeting to Nucleus
Target
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