RGS5 antibody (N-Term)

Catalog No. ABIN954533

The Rabbit Polyclonal anti-RGS5 antibody is suitable to detect RGS5 in samples from Human. It has been validated for WB and EIA.

Quick Overview for RGS5 antibody (N-Term) (ABIN954533)

Target: RGS5 (Regulator of G-Protein Signaling 5 (RGS5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS5 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-RGS5 Antibody

Binding Specificity: AA 23-53, N-Term

Specificity: This antibody recognizes Human RGS5 (N-term).

Purification: Affinity Chromatography on protein A

Immunogen: KLH conjugated synthetic peptide between 23-53 amino acids from the N-terminal region of Human RGS5. Genename: RGS5

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RGS5

Target: RGS5 (Regulator of G-Protein Signaling 5 (RGS5))

Alternative Name: RGS5

Background: This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: Regulator of G-protein signaling 5

Molecular Weight: 20946 Da

Gene ID: 8490

NCBI Accession: NP_003608

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling