SAP18 antibody (Middle Region)

Catalog No. ABIN954669

This anti-SAP18 antibody is a Rabbit Polyclonal antibody detecting SAP18 in WB and EIA. Suitable for Human.

Quick Overview for SAP18 antibody (Middle Region) (ABIN954669)

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAP18 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SAP18 Antibody

Binding Specificity: AA 57-86, Middle Region

Specificity: Recognizes SAP18 (Center).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 57-86 amino acids from the Central region of Human SAP18 Genename: SAP18

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SAP18

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Alternative Name: SAP18

Background: Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.Synonyms: 2HOR0202, Cell growth-inhibiting protein 38, GIG38, Histone deacetylase complex subunit SAP18, Sin3-associated polypeptide 18 kDa, Sin3-associated polypeptide p18

Gene ID: 10284

NCBI Accession: NP_005861