SGCD antibody (C-Term)

Catalog No. ABIN954776

The Rabbit Polyclonal anti-SGCD antibody is suitable to detect SGCD in samples from Human and Mouse. It has been validated for WB and EIA.

Quick Overview for SGCD antibody (C-Term) (ABIN954776)

Target: SGCD (Sarcoglycan, delta (35kDa Dystrophin-Associated Glycoprotein) (SGCD))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGCD antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SGCD Antibody

Binding Specificity: AA 231-261, C-Term

Specificity: Recognizes SGCD (C-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 231-261 amino acids from the C-terminal region of Human SGCD (NP_001121681.1, NP_000328.2, NP_758447.1) Genename: SGCD

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SGCD

Target: SGCD (Sarcoglycan, delta (35kDa Dystrophin-Associated Glycoprotein) (SGCD))

Alternative Name: delta-Sarcoglycan

Background: The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.Synonyms: 35DAG, 5 kDa dystrophin-associated glycoprotein, SGCD

Gene ID: 6444

NCBI Accession: NP_001121681

Pathways: Maintenance of Protein Location