SH2D4B antibody (C-Term)

Catalog No. ABIN954788

The Rabbit Polyclonal anti-SH2D4B antibody is suitable to detect SH2D4B in samples from Human. It has been validated for WB, IF, IHC (p) and EIA.

Quick Overview for SH2D4B antibody (C-Term) (ABIN954788)

Target: SH2D4B (SH2 Domain Containing 4B (SH2D4B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2D4B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-SH2D4B Antibody

Binding Specificity: AA 381-410, C-Term

Specificity: Recognizes SH2D4B (C-term)

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 381-410 amino acids from the C-terminal region of Human SH2D4B Genename: SH2D4B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SH2D4B

Target: SH2D4B (SH2 Domain Containing 4B (SH2D4B))

Alternative Name: SH2D4B

Background: SH2D4B (SH2 domain containing 4B) is a 431 amino acid protein that contains one SH2 domain, exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 10q23.1. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5 % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.Synonyms: SH2 domain-containing protein 4B

Gene ID: 387694

NCBI Accession: NP_001139191