FAM33A antibody (N-Term)

Catalog No. ABIN954814

This Rabbit Polyclonal antibody specifically detects FAM33A in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for FAM33A antibody (N-Term) (ABIN954814)

Target: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM33A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-FAM33A Antibody

Binding Specificity: AA 16-45, N-Term

Specificity: This antibody recognizes Human SKA2 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of Human SKA2 Genename: SKA2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FAM33A

Target: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Alternative Name: SKA2

Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization.Synonyms: FAM33A, Spindle and kinetochore-associated protein 2

Molecular Weight: 14188 Da

Gene ID: 348235

NCBI Accession: NP_872426

Pathways: M Phase