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SORD antibody (Middle Region)
SORD
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SORD Antibody
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Target
See all SORD Antibodies
SORD
(Sorbitol Dehydrogenase (SORD))
Binding Specificity
All epitopes for SORD antibodies
AA 210-239, Middle Region
Reactivity
All reactivities for SORD antibodies
Human
Host
All hosts for SORD antibodies
Rabbit
Clonality
All clonalities for SORD antibodies
Polyclonal
Conjugate
All conjugates for SORD antibodies
This SORD antibody is un-conjugated
Application
All applications for SORD antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human SORD (Center).
Purification
Affinity Chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of Human SORD. Genename: SORD
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for SORD
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Target
SORD
(Sorbitol Dehydrogenase (SORD))
Alternative Name
SORD (SORD Products )
Synonyms
SORD1 antibody, Sdh-1 antibody, Sdh1 antibody, Sodh-1 antibody, SDH antibody, sord antibody, MGC83437 antibody, BmSDH antibody, PSPTO0363 antibody, SODH-1 antibody, RATSDHE1 antibody, SDH2 antibody, Sdh antibody, Sdhe1 antibody, TDH antibody, 4733401P19Rik antibody, AI836084 antibody, CGI-97 antibody, SDS antibody, zgc:63674 antibody, sorbitol dehydrogenase antibody, sorbitol dehydrogenase L homeolog antibody, Sorbitol dehydrogenase antibody, serine dehydratase antibody, SBDS ribosome maturation factor antibody, SORD antibody, Sord antibody, sord.L antibody, sord antibody, Sdh antibody, LOC733025 antibody, polS antibody, RS_RS10765 antibody, sdh antibody, smoS antibody, Rsph17029_1731 antibody, Srd antibody, RSKD131_1411 antibody, SDS antibody, Sds antibody, Sbds antibody
Background
Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor. Synonyms: L-iditol 2-dehydrogenase, Sorbitol dehydrogenase
Molecular Weight
38325 Da
Gene ID
6652
NCBI Accession
NP_003095
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