SPG20 antibody (N-Term)

Catalog No. ABIN954908

The Rabbit Polyclonal anti-SPG20 antibody is suitable to detect SPG20 in samples from Human. It has been validated for WB, FACS, IHC (p) and EIA.

Quick Overview for SPG20 antibody (N-Term) (ABIN954908)

Target: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPG20 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-SPG20 Antibody

Binding Specificity: AA 24-54, N-Term

Specificity: This antibody recognizes Spartin / SPG20 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 24-54aa) of human Spartin / SPG20

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SPG20

Target: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Alternative Name: Spartin / SPG20

Background: Spartin / SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor.Synonyms: KIAA0610, Spastic paraplegia 20 protein, TAHCCP1, Trans-activated by hepatitis C virus core protein 1

Gene ID: 23111

NCBI Accession: NP_001135766

Pathways: Regulation of Cell Size, SARS-CoV-2 Protein Interactome