STXBP2 antibody (C-Term)
Quick Overview for STXBP2 antibody (C-Term) (ABIN954993)
Target
See all STXBP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 439-469, C-Term
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Specificity
- This antibody reacts to STXBP2.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 439-469 amino acids from the C-terminal region of human STXBP2
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- STXBP2 (Syntaxin Binding Protein 2 (STXBP2))
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Alternative Name
- STXBP2 / UNC18B
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Background
- STXBP2 is involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells.Synonyms: Syntaxin-binding protein 2, UNC-18B, UNC18-2, unc-18 homolog 2, unc-18 homolog B
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Molecular Weight
- 66453 Da
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Gene ID
- 6813
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NCBI Accession
- NP_001120868
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
Target
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