STX1A antibody (N-Term)
Quick Overview for STX1A antibody (N-Term) (ABIN955037)
Target
See all STX1A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 36-65, N-Term
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Specificity
- This antibody recognizes Human Syntaxin 1A / STX1A (N-term).
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Purification
- Affinity Chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 36~65 amino acids from the N-terminal region of Human STX1A Genename: STX1A
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- STX1A (Syntaxin 1A (Brain) (STX1A))
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Alternative Name
- Syntaxin 1A / STX1A
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Background
- This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis.Synonyms: Neuron-specific antigen HPC-1, STX1, Syntaxin-1A
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Molecular Weight
- 33023 Da
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Gene ID
- 6804
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NCBI Accession
- NP_001159375
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Pathways
- Peptide Hormone Metabolism, Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Target
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