TIFA antibody (N-Term)

Catalog No. ABIN955209

The Rabbit Polyclonal anti-TIFA antibody (ABIN955209) specifically detects TIFA in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for TIFA antibody (N-Term) (ABIN955209)

Target: TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIFA antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TIFA Antibody

Binding Specificity: AA 58-88, N-Term

Specificity: This antibody detects TIFA / T2BP (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 58~88 amino acids from the N-terminal region of human TIFA

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for TIFA

Target: TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))

Alternative Name: TIFA / T2BP

Background: Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.Synonyms: Putative MAPK-activating protein PM14, Putative NF-kappa-B-activating protein 20, TRAF-interacting protein with FHA domain-containing protein A, TRAF2-binding protein

Gene ID: 92610

NCBI Accession: NP_443096