TLX1 antibody (Middle Region)

Catalog No. ABIN955235

Product Details anti-TLX1 Antibody

Target: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Binding Specificity: AA 162-191, Middle Region

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLX1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects TLX1 (Center).

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human TLX1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for TLX1

Target: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Alternative Name: TLX1 (TLX1 Products)

Synonyms: Hox-11 antibody, Hox11 antibody, HOX11 antibody, TCL3 antibody, XHox11 antibody, XHox11L2 antibody, hox11 antibody, tlx1-a antibody, TLX-1 antibody, RGD1563655 antibody, SI:dZ46P4.1 antibody, Tlx-1 antibody, ztlx-1 antibody, T cell leukemia, homeobox 1 antibody, T-cell leukemia homeobox 1 antibody, T-cell leukemia homeobox 1 L homeolog antibody, T-cell leukemia, homeobox 1 antibody, Tlx1 antibody, TLX1 antibody, tlx1.L antibody, tlx1 antibody

Background: This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants.Synonyms: HOX11, Hox-11, T-cell leukemia homeobox protein 1, T-cell leukemia/lymphoma protein 3, TCL-3, TCL3, TLX-1

Gene ID: 3195

NCBI Accession: NP_005512