TNIP2 antibody (Middle Region)

Catalog No. ABIN955282

Product Details anti-TNIP2 Antibody

Target: TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))

Binding Specificity: AA 164-194, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects TNIP2 (Center).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 164-194 amino acids from the Central region of human TNIP2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for TNIP2

Target: TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))

Alternative Name: TNIP2 (TNIP2 Products)

Background: TNIP2 binds to the C-terminal zinc finger domain of A20 (TNFAIP3, MIM 191163) and is involved in activation of the ERK (see MAPK3, MIM 601795) MAP kinase pathway in various cell types (Van Huffel et al., 2001 [PubMed 11390377], Papoutsopoulou et al., 2006 [PubMed 16633345]).Synonyms: A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, ABIN2, FLIP1, Fetal liver LKB1-interacting protein, TNFAIP3-interacting protein 2

Gene ID: 79155

NCBI Accession: NP_001154999

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin