UNC5D antibody (Middle Region)

Catalog No. ABIN955452

Product Details anti-UNC5D Antibody

Target: UNC5D (Unc-5 Homolog D (UNC5D))

Binding Specificity: AA 482-511, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC5D antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects UNC5D (Center).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column; followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 482-511 amino acids from the Central region of human UNC5D

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for UNC5D

Target: UNC5D (Unc-5 Homolog D (UNC5D))

Alternative Name: UNC5D (UNC5D Products)

Background: UNC5D is receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity).Synonyms: KIAA1777, Netrin receptor UNC5D, Protein unc-5 homolog D, UNC5H4, UNQ6012/PRO34692, Unc-5 homolog 4

Gene ID: 137970

NCBI Accession: NP_543148