ZNF146 antibody (N-Term)
Quick Overview for ZNF146 antibody (N-Term) (ABIN955681)
Target
See all ZNF146 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 24-54, N-Term
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Specificity
- This antibody detects ZNF146 (N-term).
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Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse
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Purification
- Protein A column followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 24-54 amino acids from the N-terminal region of human ZNF146
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- ZNF146 (Zinc Finger Protein 146 (ZNF146))
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Alternative Name
- ZNF146 / OZF
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Background
- The ZNF146 protein is a 33 kDa Kruppel protein, composed solely of 10 zinc finger motifs. ZNF146 overexpression in tumours may alter the balance between hRap1 and other telomeric proteins, therefore ZNF146 function may be linked to telomere regulation. ZNF146 is strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. ZNF146 is overexpresseed in 80 % of colorectal cancers.Synonyms: Only zinc finger protein, Zinc finger protein 146
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Gene ID
- 7705
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NCBI Accession
- NP_001093108
Target
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