KNG1 antibody
Quick Overview for KNG1 antibody (ABIN957875)
Target
See all KNG1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Human KNG1 / Kininogen. The heavy chains in HMWK and LMWK share immunologic determinants, but they have no procoagulant activities. The light chain of HMWK is unique to this molecule and carries the entire procoagulant activity of the molecule. The antiserum does not distinct between different forms of kininogen. The presence of non-precipitating antibodies has not been assayed. /f the antiserum is to be used in non-precipitating antibody-binding assays (immunocytochemical, immunohistochemical, solid phase procedures such as EL/SA) proper controls should be included. No reaction is obtained with any other plasma protein component or serum Cross-reactivity The antiserum does not cross react with any other component of human plasma. /nter-species cross- reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail.
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Purification
- Immunoaffinity absorbed
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Immunogen
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Human kininogen
Type of Immunogen: Purified protein
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Application Notes
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Approved: ID
Usage: This product is intended for use in precipitating techniques as immunoelectrophoresis and single or double radial immunodiffusion and electroimmunodiffusion (Laurell), to identify the presence of kininogen in human plasma or other body fluids or to determine its concentration. For electroimmunodiffusion a concentration of 1-2 % of antiserum in the gel is recommended. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Sterile distilled water 1 ml
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Concentration
- Lot specific
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Buffer
- Lyophilized antiserum
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Long term: -20°C
Short term: +4°C. Avoid repeat freeze-thaw cycles.
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- KNG1 (Kininogen 1 (KNG1))
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Alternative Name
- KNG1 / Kininogen / Bradykinin
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Background
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Name/Gene ID: KNG1
Synonyms: KNG1, Bradykinin, Flaujeac factor deficiency, Fitzgerald factor, Kininogen 1, Kininogen-1, Kininogen, BDK, HMWK, KNG -
Gene ID
- 3827
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UniProt
- P01042
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Pathways
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
Target
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