TSC1 antibody

Catalog No. ABIN961783

This Mouse Monoclonal antibody specifically detects TSC1 in ELISA, WB, IHC, IHC (p) and IP. It exhibits reactivity toward Human.

Quick Overview for TSC1 antibody (ABIN961783)

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TSC1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Product Details anti-TSC1 Antibody

Specificity: Specific for the ~130-150kD Hamartin protein and shows no reactivity with the related Tuberin protein. This specificity was confirmed with Western blot testing on both Hamartin- and Tuberin-transfected cell lysates. Reactivity was confirmed with a Hamartin-transfected 293 cell line. Species cross-reactivity: human.

Purification: Protein A purified

Immunogen: Recombinant human Hamartin protein.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA (0.1 - 1 μg/mL), IHC, IHC-P (10 μg/mL), IP (5 - 10 μg/mL), WB (1 - 3 μg/mL)

Usage: Suitable for use in ELISA, Western Blot, Immunoprecipitation. ELISA: 0.1-1 μg/mL. Western Blot: 1-3 μg/mL. Immunoprecipitation: 5-10 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Target Details for TSC1

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Alternative Name: Hamartin / TSC1

Background: Name/Gene ID: TSC1

Synonyms: TSC1, LAM, Tuberous sclerosis 1 protein, Tuberous sclerosis 1, Hamartin, KIAA0243, TSC, Tumor suppressor

Gene ID: 7248

UniProt: Q92574

Pathways: RTK Signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation