Dopamine d2 Receptor antibody (N-Term)

Catalog No. ABIN962101

This Rabbit Polyclonal antibody specifically detects Dopamine d2 Receptor in WB, IHC and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Dopamine d2 Receptor antibody (N-Term) (ABIN962101)

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dopamine d2 Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Dopamine d2 Receptor Antibody

Binding Specificity: N-Term

Specificity: Recognizes rat Dopamine Receptor, D2R. Species sequence homology: mouse (100 % ), human, bovine (90 %), canine (72 %). Cross-react with human (CNS and peripheral).

Purification: Immunoaffinity purified

Immunogen: An 11 aa peptide near the N-terminus ligand binding domain of rat D2R. Conjugated to KLH.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (0.5 - 1 μg/mL), IHC, WB (1 - 10 μg/mL)

Usage: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Western Blot: 1-10 μg/mL. (ECL). ELISA: 0.5-1 μg/mL. Control peptide can be used to coat the plates at 1 μg/mL and detected with antibodies.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Reconstitute with sterile PBS.

Concentration: Lot specific

Buffer: 0.1 % BSA

Handling Advice: avoid freeze thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Target Details for Dopamine d2 Receptor

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Alternative Name: DRD2 / Dopamine Receptor D2

Background: Name/Gene ID: DRD2
Subfamily: Dopamine
Family: GPCR

Synonyms: DRD2, D2 dopamine receptor, D2R, Dopamine receptor D2 isoform, Dopamine 2 receptor, D(2) dopamine receptor, D2DR, Dopamine D2 receptor, Dopamine receptor D2

Gene ID: 1813

UniProt: P14416

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity