CBP antibody (AA 2071-2091)

Catalog No. ABIN962158

This Mouse Monoclonal antibody specifically detects CBP in IHC, IF and IHC (p). It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for CBP antibody (AA 2071-2091) (ABIN962158)

Target: CBP (CREBBP) (CREB Binding Protein (CREBBP))

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This CBP antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CBP Antibody

Binding Specificity: AA 2071-2091

Specificity: Recognizes p300 and CBP. p300 and CBP differ by three noncontiguous residues within the 21 amino acid epitope region. A difference that does not detectably affect the reactivity of This antibody. Species cross-reactivity: human, monkey, mink, mouse, and rat.

Purification: Protein A purified

Immunogen: Purified p300 protein. Epitope: aa2071-2091.

Isotype: IgG2b

Application Details

Application Notes: Approved: IF, IHC, IHC-P (1:25)

Usage: Suitable for use in Immunofluorescence and Immunohistochemistry. Immunohistochemistry (Formalin/paraffin): 1:25-1:50 for 20 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Positive control: Tonsil.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.2 % BSA, 0.09 % sodium azide, 40 % glycerol. Sourced from ascites.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CBP

Target: CBP (CREBBP) (CREB Binding Protein (CREBBP))

Alternative Name: CREBBP / CBP

Background: Name/Gene ID: CREBBP

Synonyms: CREBBP, CREB binding protein, CREB-binding protein, KAT3A, RSTS, Rubinstein-Taybi syndrome, RTS, CBP

Gene ID: 1387

UniProt: Q92793

Pathways: TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha