HCN1 antibody (AA 778-910)

Catalog No. ABIN962167

This Mouse Monoclonal antibody specifically detects HCN1 in WB, IHC, IP, ICC and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for HCN1 antibody (AA 778-910) (ABIN962167)

Target: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This HCN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: S70-28

Product Details anti-HCN1 Antibody

Binding Specificity: AA 778-910

Brand: IHC-plus™

Specificity: Detects ~100 kD protein. No cross reactivity against HCN2.

Purification: Protein G purified from tissue culture supernatant

Immunogen: Fusion protein amino acids 778-910 (C terminus) of rat HCN1, accession number Q9JKB0.

Type of Immunogen: Fusion protein

Isotype: IgG1

Application Details

Application Notes: Approved: ICC (0.1 - 1 μg/mL), IHC, IHC-P (1:50), IP (1 - 10 μg/mL), WB (1 - 10 μg/mL)

Usage: Western Blot: Use the lysate in SDS buffer but without boiling, incubating for 20 mins at 37 °C instead.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 50 % glycerol, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for HCN1

Target: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Alternative Name: HCN1

Background: Name/Gene ID: HCN1
Subfamily: Potassium channel - cyclic nucleotide gated
Family: Ion Channel

Synonyms: HCN1, BCNG1, BCNG-1, HAC2, HAC-2

Gene ID: 348980

UniProt: O60741

Pathways: Asymmetric Protein Localization