BCL2L1 antibody

Catalog No. ABIN965653

This Rabbit Polyclonal antibody specifically detects BCL2L1 in IHC. It exhibits reactivity toward Human, Mouse and Rat. It has been mentioned in 2+ publications

Quick Overview for BCL2L1 antibody (ABIN965653)

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-BCL2L1 Antibody

Specificity: BCL-XL (Ab-62) antibody detects endogenous levels of total BCL-XL protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: This antiserum was produced against synthesized non-phosphopeptide derived from human BCL-XL around the phosphorylation site of serine 62 (A-D-SP-P-A).

Application Details

Application Notes: WB: 1:500~1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-BCL2L1 antibody (ABIN965653)

Sattler, Liang, Nettesheim, Meadows, Harlan, Eberstadt, Yoon, Shuker, Chang, Minn, Thompson, Fesik: "Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis." in: Science (New York, N.Y.), Vol. 275, Issue 5302, pp. 983-6, (1997) (PubMed).

Muchmore, Sattler, Liang, Meadows, Harlan, Yoon, Nettesheim, Chang, Thompson, Wong, Ng, Fesik: "X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death." in: Nature, Vol. 381, Issue 6580, pp. 335-41, (1996) (PubMed).

Target Details for BCL2L1

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Alternative Name: BCL-XL

Pathways: Apoptosis, Negative Regulation of intrinsic apoptotic Signaling