MME antibody

Catalog No. ABIN965761

This Mouse Monoclonal antibody specifically detects MME in FACS, IHC (fro) and IHC (af). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for MME antibody (ABIN965761)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MME antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Acetone-fixed) (IHC (af))

Clone: B396 (FR4D11)

Product Details anti-MME Antibody

Specificity: This antibody reacts with human common acute lymphoblastic leukemia antigen, a 100 kD glycoprotein.

Purification: Purified.

Immunogen: RAJI (Burkitt's lymphoma) cells.

Isotype: IgG1

Application Details

Application Notes: Immunofluorescence: 5-20 ug/mL.
Flow cytometry: 1-5 ug/10^6 cells.
Immunohistochemistry: 5-20 ug/mL on frozen sections using avidin-biotin system. This antibody was not quality controlled in flow cytometry.
Staining Procedure: This antibody can be used on acetone fixed frozen cryostat sections.

Comment:

Recommended Positive Control: Tonsil, Lymph Node, and Small Intestine

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/ml.

Buffer: 50 mM Sodium Borate, 150 mM Sodium Chloride, 20% Glycerol, pH 8.0

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-MME antibody (ABIN965761)

Mizoguchi: "[Diagnosis and therapy of megakaryoblastic leukemia]." in: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, Vol. 82, Issue 7, pp. 1053-7, (1993) (PubMed).

Pezzutto, Dörken, Rabinovitch, Ledbetter, Moldenhauer, Clark: "CD19 monoclonal antibody HD37 inhibits anti-immunoglobulin-induced B cell activation and proliferation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 138, Issue 9, pp. 2793-9, (1987) (PubMed).

Target Details for MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name: CD10,CALLA

Target Type: Chemical

Gene ID: 4311

Pathways: RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration