Endoglin antibody
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- Target See all Endoglin (ENG) Antibodies
- Endoglin (ENG)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Endoglin antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human CD105 expressed in E. Coli.
- Clone
- 3A9
- Isotype
- IgG1
- Top Product
- Discover our top product ENG Primary Antibody
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- Application Notes
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Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Format
- Liquid
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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Endoglin (CD105) as a urinary and serum marker of prostate cancer." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 3, pp. 664-9, (2008) (PubMed).
: "Pharmacophore-based virtual screening." in: Current medicinal chemistry, Vol. 15, Issue 10, pp. 1018-24, (2008) (PubMed).
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Endoglin (CD105) as a urinary and serum marker of prostate cancer." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 3, pp. 664-9, (2008) (PubMed).
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- Target
- Endoglin (ENG)
- Alternative Name
- CD105 (ENG Products)
- Background
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This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
Synonyms: ENG, END, ORW, HHT1, ORW1, CD105, FLJ41744 - Molecular Weight
- 71kDa
- Gene ID
- 2022
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