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CD34 antibody

This anti-CD34 antibody is a Monoclonal antibody detecting CD34 in WB, IF and ELISA. Suitable for Human. This Primary Antibody has been cited in 3+ publications.
Catalog No. ABIN965787

Quick Overview for CD34 antibody (ABIN965787)

Target

See all CD34 Antibodies
CD34

Reactivity

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Human

Host

Please inquire

Clonality

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Monoclonal

Conjugate

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This CD34 antibody is un-conjugated

Application

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Western Blotting (WB), Immunofluorescence (IF), ELISA
  • Specificity

    Ni-NTA purified truncated recombinant CD34 expressed in E. Coli strain BL21 (DE3).

    Purification

    Antibodies are purified by protein A affinity chromatography

    Isotype

    IgG
  • Application Notes

    Dilution Western Blot: 1: 200- 1: 1,000
    IF: 1:25- 1: 100
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Storage

    -20 °C
  • Sho, Sho, Nanjo, Kawamura, Masuda, Dalman: "Hemodynamic regulation of CD34+ cell localization and differentiation in experimental aneurysms." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 24, Issue 10, pp. 1916-21, (2004) (PubMed).

    Krause, Ito, Fackler, Smith, Collector, Sharkis, May: "Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells." in: Blood, Vol. 84, Issue 3, pp. 691-701, (1994) (PubMed).

    Satterthwaite, Burn, Le Beau, Tenen: "Structure of the gene encoding CD34, a human hematopoietic stem cell antigen." in: Genomics, Vol. 12, Issue 4, pp. 788-94, (1992) (PubMed).

  • Target

    CD34

    Alternative Name

    CD34

    Background

    CD34 is a transmembrane glycoprotein with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells, endothelial cells and some fibroblasts. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells. CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.

    Gene ID

    947
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