CDCA5 antibody (N-Term)

Catalog No. ABIN965837

The Rabbit Polyclonal anti-CDCA5 antibody is suitable to detect CDCA5 in samples from Human. It has been validated for IHC.

Quick Overview for CDCA5 antibody (N-Term) (ABIN965837)

Target: CDCA5 (Cell Division Cycle Associated 5 (CDCA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA5 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CDCA5 Antibody

Binding Specificity: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human CDCA5 (Cell division cycle associated 5)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CDCA5

Target: CDCA5 (Cell Division Cycle Associated 5 (CDCA5))

Alternative Name: CDCA5

Background: CDCA5(Cell division cycle associated 5) is a regulator of sister chromatid cohesion in mitosis. CDCA5 may act by regulating the ability of the cohesin complex to mediate sister chromatid cohesion, perhaps by altering the nature of the interaction of cohesin with the chromosomes. CDCA5 interacts with the APC/C complex. CDCA5 is found in a complex with cohesin components SMC1L1, SMC3L1 and RAD21, PDS5A/APRIN and PDS5B/SCC-112. The interaction with cohesin subunits is probably indirect, and is weak. CDCA5 was named Sororin after the Latin word soror, which means sister, because of its critical role in sister chromatid cohesion.

Pathways: Chromatin Binding