Cofilin antibody

Catalog No. ABIN965911

This Rabbit Polyclonal antibody specifically detects Cofilin in IHC. It exhibits reactivity toward Human, Mouse and Rat. It has been mentioned in 2+ publications

Quick Overview for Cofilin antibody (ABIN965911)

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cofilin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Cofilin Antibody

Specificity: Cofilin (Ab-1022) antibody detects endogenous levels of total cofilin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human cofilin around the phosphorylation site of serine 3.

Application Details

Application Notes: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-Cofilin antibody (ABIN965911)

Kobayashi, Nishita, Mishima, Ohashi, Mizuno: "MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration." in: The EMBO journal, Vol. 25, Issue 4, pp. 713-26, (2006) (PubMed).

Wang, Shibasaki, Mizuno: "Calcium signal-induced cofilin dephosphorylation is mediated by Slingshot via calcineurin." in: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 12683-9, (2005) (PubMed).

Target Details for Cofilin

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Alternative Name: Cofilin

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events