EIF5A2 antibody (C-Term)

Catalog No. ABIN966053

Product Details anti-EIF5A2 Antibody

Target: EIF5A2 (Eukaryotic Translation Initiation Factor 5A2 (EIF5A2))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF5A2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human EIF5A2

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-EIF5A2 antibody (ABIN966053)

Luo, Hua, Rao, Liao, Kung, Zeng, Guan, Chen, Xie: "Overexpression of EIF-5A2 predicts tumor recurrence and progression in pTa/pT1 urothelial carcinoma of the bladder." in: Cancer science, Vol. 100, Issue 5, pp. 896-902, (2009) (PubMed).

Chen, Luo, Hua, Zhou, Lin, Kung, Zeng, Guan, Xie: "Overexpression of EIF-5A2 is an independent predictor of outcome in patients of urothelial carcinoma of the bladder treated with radical cystectomy." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 2, pp. 400-8, (2009) (PubMed).

Yang, Xie, Liu, Luo, Li, Hua, Wu, Kung, Zeng, Guan: "Expression and amplification of eIF-5A2 in human epithelial ovarian tumors and overexpression of EIF-5A2 is a new independent predictor of outcome in patients with ovarian carcinoma." in: Gynecologic oncology, Vol. 112, Issue 2, pp. 314-8, (2009) (PubMed).

Xie, Ma, Pan, Wu, Liu, Wu, Kung, Guan: "Overexpression of EIF-5A2 is associated with metastasis of human colorectal carcinoma." in: Human pathology, Vol. 39, Issue 1, pp. 80-6, (2007) (PubMed).

Ojima, Inoue, Miki, Mori, Kusunoki: "Effectiveness of gene expression profiling for response prediction of rectal cancer to preoperative radiotherapy." in: Journal of gastroenterology, Vol. 42, Issue 9, pp. 730-6, (2007) (PubMed).

Andersen, Lam, Leung, Ong, Lyon, Lamond, Mann: "Nucleolar proteome dynamics." in: Nature, Vol. 433, Issue 7021, pp. 77-83, (2005) (PubMed).

Guan, Fung, Ma, Lau, Tai, Xie, Zhang, Hu, Wu, Fang, Sham: "Oncogenic role of eIF-5A2 in the development of ovarian cancer." in: Cancer research, Vol. 64, Issue 12, pp. 4197-200, (2004) (PubMed).

Target Details for EIF5A2

Target: EIF5A2 (Eukaryotic Translation Initiation Factor 5A2 (EIF5A2))

Alternative Name: EIF5A2 (EIF5A2 Products)

Synonyms: EIF5A2 antibody, EIF5A antibody, zgc:55504 antibody, zgc:77429 antibody, wu:fb05b06 antibody, wu:fc23f04 antibody, wu:fc61c10 antibody, EIF-5A2 antibody, eIF5AII antibody, 9630038B20 antibody, eukaryotic translation initiation factor 5A2 antibody, eukaryotic translation initiation factor 5A3 antibody, EIF5A2 antibody, eif5a2 antibody, LOC100499632 antibody, Eif5a2 antibody

Background: EIF5A2 (Eukaryotic initiation factor 5A ) stimulates ribosomal peptidyltransferase activity, transport of HIV-1-mRNAs and binds exportins 1 and 4. Contains hypusine at lys 50. Human EIF5A1 and EIF5A2 encode two isoforms: eIF5AI and eIF5AII. Increased expression of EIF-5A2 in ovarian carcinoma may represent an acquired malignant phenotypic feature of tumor cells. Overexpression of EIF5A2 is an independent molecular marker for shortened survival time of patients with ovarian carcinoma.