Glutamate Receptor 3 antibody

Catalog No. ABIN966225

This anti-Glutamate Receptor 3 antibody is a Mouse Monoclonal antibody detecting Glutamate Receptor 3 in WB, ELISA and IHC. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for Glutamate Receptor 3 antibody (ABIN966225)

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Glutamate Receptor 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 1D2

Product Details anti-Glutamate Receptor 3 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human GRIA3 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-Glutamate Receptor 3 antibody (ABIN966225)

Am: "Trust in Nanotechnology? On Trust as Analytical Tool in Social Research on Emerging Technologies." in: Nanoethics, Vol. 5, Issue 1, pp. 15-28, (2011) (PubMed).

Target Details for Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Alternative Name: GRIA3

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
Synonyms: GLUR3, GLURC, GluA3, MRX94, GLUR-C, GLUR-K3

Molecular Weight: 101kDa

Gene ID: 2892

Pathways: PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane