Purified by antigen-specific affinity chromatography.
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human INHBB (Inhibin beta B chain precursor)
actbb antibody, actbetaB antibody, inhibin antibody, inhibin, beta B antibody, inhibin beta B L homeolog antibody, inhibin beta B subunit antibody, inhibin beta B antibody, inhibin beta-B antibody, inhibin beta B chain antibody, inhbb antibody, inhbb.L antibody, INHBB antibody, Inhbb antibody, LOC100719829 antibody
Background
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B.