KSHVK8a antibody

Catalog No. ABIN966463

Product Details

Target: KSHVK8a

Reactivity: Human Herpesvirus 8 (HHV-8)

Host: Please inquire

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Specificity: Ni-NTA purified recombinant human KSHV K8 expressed in E. Coli strain BL21 (DE3).

Purification: Crude ascites.

Isotype: IgG2a

Application Details

Application Notes: Western Blot: Dilution 1: 500- 1,000
ICC: Dilution 1:50- 1: 100
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Storage: -20 °C

Target Details

Target: KSHVK8a

Target Type: Viral Protein

Background: Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV K8 and K8.1 open reading frames are juxtaposed and span from nucleotide (nt) 74850 to 76695 of the virus genome. A K8 pre-mRNA overlaps the entire K8.1 coding region, and alternative splicing of KSHV K8 and K8.1 pre-mRNAs each produces three isoforms (à, á and x) of the mRNAs.