Myoglobin antibody

Catalog No. ABIN966633

Product Details anti-Myoglobin Antibody

Target: Myoglobin (MB)

Reactivity: Human

Host: Please inquire

Clonality: Monoclonal

Conjugate: This Myoglobin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: Ni-NTA purified truncated recombinant Myoglobin expressed in E. Coli strain BL21 (DE3)

Isotype: IgG1

Application Details

Application Notes: Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Storage: -20 °C

References for anti-Myoglobin antibody (ABIN966633)

Flögel, Laussmann, Gödecke, Abanador, Schäfers, Fingas, Metzger, Levkau, Jacoby, Schrader: "Lack of myoglobin causes a switch in cardiac substrate selection." in: Circulation research, Vol. 96, Issue 8, pp. e68-75, (2005) (PubMed).

Ordway, Garry: "Myoglobin: an essential hemoprotein in striated muscle." in: The Journal of experimental biology, Vol. 207, Issue Pt 20, pp. 3441-6, (2004) (PubMed).

Target Details for Myoglobin

Target: Myoglobin (MB)

Alternative Name: Myoglobin (MB Products)

Synonyms: PVALB antibody, AI325109 antibody, zgc:65819 antibody, zgc:77764 antibody, MB antibody, DKFZp468H096 antibody, myg antibody, mb antibody, MYF4 antibody, bHLHc3 antibody, myo antibody, Myoglobin antibody, myoglobin antibody, myogenin antibody, MB antibody, Mb antibody, mb antibody, myg antibody, Myog antibody

Background: Myoglobin (MB), with 154-amino acid protein (about 17kDa), is a member of the globin superfamily and expression of myoglobin is highest in skeletal and cardiac muscle. Functionally, myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia. Myoglobin is also thought to buffer intracellular O2 concentration when muscle activity increases and to facilitate intracellular O2 diffusion by providing a parallel path that augments simple diffusion of dissolved O2. Furthermore, myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.

Gene ID: 4151

Pathways: Brown Fat Cell Differentiation