ERK1/2 antibody

Catalog No. ABIN966752

There are 4+ publications for this product available. The Rabbit Polyclonal anti-ERK1/2 antibody is suitable to detect ERK1/2 in samples from Human, Mouse and Rat. It has been validated for IHC.

Quick Overview for ERK1/2 antibody (ABIN966752)

Target: ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERK1/2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-ERK1/2 Antibody

Specificity: P44/42 MAP Kinase (Ab-202) antibody detects endogenous levels of total p44/42 MAP Kinase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Application Details

Application Notes: WB: 1:500~1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-ERK1/2 antibody (ABIN966752)

Yu, Mizumoto, Tokinaga, Ogawa, Hatano: "The inhibitory effects of sevoflurane on angiotensin II- induced, p44/42 mitogen-activated protein kinase-mediated contraction of rat aortic smooth muscle." in: Anesthesia and analgesia, Vol. 101, Issue 2, pp. 315-21, table of contents, (2005) (PubMed).

Perez, Nolan: "Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry." in: Nature biotechnology, Vol. 20, Issue 2, pp. 155-62, (2002) (PubMed).

Hannken, Schroeder, Zahner, Stahl, Wolf: "Reactive oxygen species stimulate p44/42 mitogen-activated protein kinase and induce p27(Kip1): role in angiotensin II-mediated hypertrophy of proximal tubular cells." in: Journal of the American Society of Nephrology : JASN, Vol. 11, Issue 8, pp. 1387-97, (2000) (PubMed).

Ihn, Tamaki: "Oncostatin M stimulates the growth of dermal fibroblasts via a mitogen-activated protein kinase-dependent pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 4, pp. 2149-55, (2000) (PubMed).

Target Details for ERK1/2

Target: ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

Alternative Name: p44/42 MAP Kinase