Progesterone Receptor antibody (AA 730-871)

Catalog No. ABIN966829

This Mouse Monoclonal antibody specifically detects Progesterone Receptor in WB and ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for Progesterone Receptor antibody (AA 730-871) (ABIN966829)

Target: Progesterone Receptor (PGR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 8A11H1

Product Details anti-Progesterone Receptor Antibody

Binding Specificity: AA 730-871

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of PGR (aa730-871) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-Progesterone Receptor antibody (ABIN966829)

Polo, José Galindo, Martínez, Alvarez, Arévalo, Asensi, Cánoves, Cáncer, Collazos, Estrada, Gómez-Candela, Johnston, Locutura, López-Aldeguer, Lozano, Miralles, Muñoz-Sanz, Ortega, Pascua, Pedrol, Pulido, San Martín, Sanz, Viciana, Chamorro,: "[Recommendations of the Study Group for Metabolic Alterations/Secretariat for the National AIDS Plan (GEAM/SPNS) on the management of metabolic and morphologic alterations in patients with HIV infection]." in: Enfermedades infecciosas y microbiología clínica, Vol. 24, Issue 2, pp. 96-117, (2006) (PubMed).

Buser, Gass-Handel, Wyszomierski, Doppler, Leonhardt, Schaack, Rosen, Watkin, Anderson, Edwards: "Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 21, Issue 1, pp. 106-25, (2006) (PubMed).

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: PGR

Background: PGR: progesterone receptor. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.
Synonyms: PR, NR3C3, PGR

Gene ID: 5241

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration