RAB3D antibody

Catalog No. ABIN966928

Product Details anti-RAB3D Antibody

Target: RAB3D (RAB3D, Member RAS Oncogene Family (RAB3D))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB3D antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with whole purified recombinant protein of human Rab 3D

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-RAB3D antibody (ABIN966928)

Curie, Sacco, Bussy, de Saint Martin, Boddaert, Chanraud, Meresse, Chelly, Zilbovicius, des Portes: "Impairment of cerebello-thalamo-frontal pathway in Rab-GDI mutated patients with pure mental deficiency." in: European journal of medical genetics, Vol. 52, Issue 1, pp. 6-13, (2009) (PubMed).

Caswell, Spence, Parsons, White, Clark, Cheng, Mills, Humphries, Messent, Anderson, McCaffrey, Ozanne, Norman: "Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments." in: Developmental cell, Vol. 13, Issue 4, pp. 496-510, (2007) (PubMed).

Target Details for RAB3D

Target: RAB3D (RAB3D, Member RAS Oncogene Family (RAB3D))

Alternative Name: Rab 3D (RAB3D Products)

Synonyms: RAB3D antibody, rab3d antibody, fi17a03 antibody, wu:fi17a03 antibody, C130057E11Rik antibody, D2-2 antibody, GOV antibody, RAB16 antibody, RAD3D antibody, RAB3D, member RAS oncogene family antibody, RAB3D, member RAS oncogene family S homeolog antibody, Ras-related protein Rab-3D antibody, RAB3D, member RAS oncogene family, a antibody, RAB3D antibody, rab3d.S antibody, rab3d antibody, rab3da antibody, Rab3d antibody

Background: Members of the Rab 3 subfamily of low-molecular-mass GTP-binding proteins have been functionally implicated in regulated exocytosis. Rab 3D mRNA is predominantly expressed in white adipose tissue and, coincident with GLUT4, increases upon differentiation of 3T3-L1 -broblasts into insulin-responsive adipocytes [19]. Rab 3D displays close structural similarities with Rab 3A, an isoform which has been functionally implicated in regulated exocytosis in various cell types.