S100A1 antibody

Catalog No. ABIN966986

There are 3+ publications for this product available. The Monoclonal anti-S100A1 antibody is suitable to detect S100A1 in samples from Human. It has been validated for ELISA.

Quick Overview for S100A1 antibody (ABIN966986)

Target: S100A1 (S100 Calcium Binding Protein A1 (S100A1))

Reactivity: Human

Host: Please inquire

Clonality: Monoclonal

Conjugate: This S100A1 antibody is un-conjugated

Application: ELISA

Product Details anti-S100A1 Antibody

Specificity: Ni-NTA purified truncated recombinant S100A expressed in E. Coli strain BL21 (DE3)

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Dilution ELISA: Propose dilution 1: 10,000 Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

References for anti-S100A1 antibody (ABIN966986)

Koenig, Wojcieszyn, Weeks, Modiano: "Expression of S100a, vimentin, NSE, and melan A/MART-1 in seven canine melanoma cells lines and twenty-nine retrospective cases of canine melanoma." in: Veterinary pathology, Vol. 38, Issue 4, pp. 427-35, (2001) (PubMed).

Hoyaux, Decaestecker, Heizmann, Vogl, Schäfer, Salmon, Kiss, Pochet: "S100 proteins in Corpora amylacea from normal human brain." in: Brain research, Vol. 867, Issue 1-2, pp. 280-8, (2000) (PubMed).

Pingerelli, Mizukami, Wagner, Bartnicki, Oliver: "Investigation of the Ca2(+)-dependent interaction of trifluoperazine with S100a: a 19F NMR and circular dichroism study." in: Journal of protein chemistry, Vol. 9, Issue 2, pp. 169-75, (1990) (PubMed).

Target Details for S100A1

Target: S100A1 (S100 Calcium Binding Protein A1 (S100A1))

Alternative Name: S100A

Background: S100 calcium binding protein A1 (S100-alpha/ S100A1), The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.

Gene ID: 6271

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins