SLC30A6 antibody (C-Term)

Catalog No. ABIN967277

There are 3+ publications for this product available. The Rabbit Polyclonal anti-SLC30A6 antibody is suitable to detect SLC30A6 in samples from Mouse and Rat. It has been validated for IHC.

Quick Overview for SLC30A6 antibody (C-Term) (ABIN967277)

Target: SLC30A6 (Solute Carrier Family 30 (Zinc Transporter), Member 6 (SLC30A6))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC30A6 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-SLC30A6 Antibody

Binding Specificity: C-Term

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to very C-terminal residues of mouse Znt6 (Zinc transporter 6) protein

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-SLC30A6 antibody (ABIN967277)

Smith, Xiong, Markesbery, Lovell: "Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain." in: Neuroscience, Vol. 140, Issue 3, pp. 879-88, (2006) (PubMed).

Seve, Chimienti, Devergnas, Favier: "In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression." in: BMC genomics, Vol. 5, Issue 1, pp. 32, (2004) (PubMed).

Huang, Kirschke, Gitschier: "Functional characterization of a novel mammalian zinc transporter, ZnT6." in: The Journal of biological chemistry, Vol. 277, Issue 29, pp. 26389-95, (2002) (PubMed).

Target Details for SLC30A6

Target: SLC30A6 (Solute Carrier Family 30 (Zinc Transporter), Member 6 (SLC30A6))

Alternative Name: Znt6

Background: Znt6 (Zinc transporter 6) functions Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. Znt6 interacts with ZNT5. Znt6 is localized in Golgi apparatus, trans-Golgi network membrane, It is a multi-pass membrane protein and is expressed in brain and liver, and to a lower extent also in lung. Znt6 seems to have lost most of the histidine residues in the loop between the fourth and fifth transmembrane regions and appears to exert transport function by forming complexes with ZNT5. Znt6 belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family and SLC30A subfamily.
Synonyms: Slc30a6 (Solute carrier family 30 member 6)

Pathways: Peptide Hormone Metabolism, SARS-CoV-2 Protein Interactome