ANXA6 antibody (AA 1-673)

Catalog No. ABIN967890

Cited in 5+ publications. The Mouse Monoclonal anti-ANXA6 antibody (Clone 73-Annexin VI) (ABIN967890) specifically detects ANXA6 in WB, IHC, IF and IP. The antibody is reactive with Human and Rat samples.

Quick Overview for ANXA6 antibody (AA 1-673) (ABIN967890)

Target: ANXA6 (Annexin A6 (ANXA6))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ANXA6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 73-Annexin VI

Product Details anti-ANXA6 Antibody

Binding Specificity: AA 1-673

Cross-Reactivity: Rat (Rattus)

Characteristics: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Human Annexin VI aa. 1-673

Isotype: IgG1

Application Details

Comment:

Related Products: ABIN968537, ABIN967389

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store undiluted at -20°C.

References for anti-ANXA6 antibody (ABIN967890)

Chen, Coustan-Smith, Suzuki, Neale, Mihara, Pui, Campana: "Identification of novel markers for monitoring minimal residual disease in acute lymphoblastic leukemia." in: Blood, Vol. 97, Issue 7, pp. 2115-20, (2001) (PubMed).

Babiychuk, Draeger: "Annexins in cell membrane dynamics. Ca(2+)-regulated association of lipid microdomains." in: The Journal of cell biology, Vol. 150, Issue 5, pp. 1113-24, (2000) (PubMed).

Babiychuk, Palstra, Schaller, Kämpfer, Draeger: "Annexin VI participates in the formation of a reversible, membrane-cytoskeleton complex in smooth muscle cells." in: The Journal of biological chemistry, Vol. 274, Issue 49, pp. 35191-5, (2000) (PubMed).

Yu, Cassara, Weller: "Phosphatidylinositide 3-kinase localizes to cytoplasmic lipid bodies in human polymorphonuclear leukocytes and other myeloid-derived cells." in: Blood, Vol. 95, Issue 3, pp. 1078-85, (2000) (PubMed).

Crompton, Moss, Crumpton: "Diversity in the lipocortin/calpactin family." in: Cell, Vol. 55, Issue 1, pp. 1-3, (1988) (PubMed).

Target Details for ANXA6

Target: ANXA6 (Annexin A6 (ANXA6))

Alternative Name: Annexin VI

Background: Annexins are a widely expressed family of Ca[2+] and phospholipid-binding proteins. At least ten have been identified in mammalian tissues. They have also been identified in Drosophila, Hydra, and Dictyostelium. Annexin VI is a 70 kDa member of the annexin family. While most of the other annexin family members have a four amino acid sequence repeat, Annexin VI displays an eight residue repeat. It is a widely expressed protein, found in lymphocytes, neurons, and many other cell types. Work on annexins has addressed the possible role of Annexin VI in various stages of the endocytic pathway. Some studies suggest that Annexin VI is required for coated-vesicle budding. However, other research directly contradicts this data. Thus, the role of Annexin VI is still under investigation.

Molecular Weight: 70 kDa