Endoglin antibody

Catalog No. ABIN969012

This anti-Endoglin antibody is a Mouse Monoclonal antibody detecting Endoglin in FACS, IHC, ELISA and ICC. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for Endoglin antibody (ABIN969012)

Target: Endoglin (ENG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: 3A9

Product Details anti-Endoglin Antibody

Purpose: CD105 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CD105 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Endoglin antibody (ABIN969012)

Valeria, Maddalena, Enrica, Onofrio, Gaetano: "Endoglin (CD105) expression in the human heart throughout gestation: an immunohistochemical study." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 15, Issue 10, pp. 1018-26, (2008) (PubMed).

Fujita, Ewing, Chan, Mangold, Partin, Isaacs, Pavlovich: "Endoglin (CD105) as a urinary and serum marker of prostate cancer." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 3, pp. 664-9, (2008) (PubMed).

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105

Background: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.

Molecular Weight: 71 kDa

UniProt: P17813