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Cytokeratin 18 antibody (AA 391-483)

KRT18 Reactivity: Human WB, IHC, ELISA Host: Mouse Monoclonal 4D11E4 unconjugated
Catalog No. ABIN969075
  • Target See all Cytokeratin 18 (KRT18) Antibodies
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    Binding Specificity
    • 25
    • 16
    • 15
    • 14
    • 13
    • 12
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 391-483
    Reactivity
    • 240
    • 129
    • 95
    • 42
    • 34
    • 27
    • 22
    • 19
    • 19
    • 18
    • 16
    • 14
    • 14
    • 14
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    Human
    Host
    • 148
    • 124
    • 3
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 142
    • 135
    • 1
    Monoclonal
    Conjugate
    • 146
    • 23
    • 22
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Cytokeratin 18 antibody is un-conjugated
    Application
    • 220
    • 102
    • 86
    • 76
    • 71
    • 56
    • 54
    • 40
    • 38
    • 27
    • 27
    • 19
    • 8
    • 8
    • 7
    • 6
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Purpose
    Cytokeratin 18 Antibody
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human Cytokeratin 18 (aa391-483) expressed in E. Coli.
    Clone
    4D11E4
    Isotype
    IgG2b
    Top Product
    Discover our top product KRT18 Primary Antibody
  • Application Notes
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Cheng, Liu, Ho, Chao, Pei, Hsu, Yeh, Ho, Tsai, Lai: "The influence of plectin deficiency on stability of cytokeratin18 in hepatocellular carcinoma." in: Journal of molecular histology, Vol. 39, Issue 2, pp. 209-16, (2008) (PubMed).

    Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: "Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast." in: Cancer genetics and cytogenetics, Vol. 178, Issue 2, pp. 94-103, (2007) (PubMed).

  • Target
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    Alternative Name
    Cytokeratin 18 (KRT18 Products)
    Background

    Description: Cytokeratin 18, also known as CK18, CYK18, KRT18. Entrez Protein NP_000215. It encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

    Aliases: CK18, CYK18, KRT18

    Molecular Weight
    48kDa
    Gene ID
    3875
    HGNC
    3875
    UniProt
    P05783
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
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