EGR1 antibody (AA 282-433)

Catalog No. ABIN969092

The Mouse Monoclonal anti-EGR1 antibody has been validated for ELISA. It is suitable to detect EGR1 in samples from Human. There are 2+ publications available.

Quick Overview for EGR1 antibody (AA 282-433) (ABIN969092)

Target: EGR1 (Early Growth Response 1 (EGR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EGR1 antibody is un-conjugated

Application: ELISA

Clone: 8A6

Product Details anti-EGR1 Antibody

Binding Specificity: AA 282-433

Purpose: EGR1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human EGR1(aa282-433) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-EGR1 antibody (ABIN969092)

Chan, Lee, Ho, Wong, Lam, Tang, Chan, Abdullah, Wong, Lam: "High-level expression of early growth response-1 and association of polymorphism with total IgE and atopy in allergic rhinitis adults." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 411, Issue 1-2, pp. 67-71, (2009) (PubMed).

Choi, Kim, Lim, Lee, Shin: "Transcriptional activation of the human Klotho gene by epidermal growth factor in HEK293 cells; role of Egr-1." in: Gene, Vol. 450, Issue 1-2, pp. 121-7, (2009) (PubMed).

Target Details for EGR1

Target: EGR1 (Early Growth Response 1 (EGR1))

Alternative Name: EGR1

Background: The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

Molecular Weight: 57.5 kDa

Gene ID: 1958

UniProt: P18146

Pathways: Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity