EPH Receptor B4 antibody

Catalog No. ABIN969108

This anti-EPH Receptor B4 antibody is a Mouse Monoclonal antibody detecting EPH Receptor B4 in ELISA and ICC. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for EPH Receptor B4 antibody (ABIN969108)

Target: EPH Receptor B4 (EPHB4)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor B4 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC)

Clone: 5B5

Product Details anti-EPH Receptor B4 Antibody

Purpose: EPHB4 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant extracellular fragment of human EPHB4 fused with hIgGFc tag expressed in HEK293 cell line.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-EPH Receptor B4 antibody (ABIN969108)

Tachibana, Tonomoto, Hyakudomi, Hyakudomi, Hattori, Ueda, Kinugasa, Yoshimura: "Expression and prognostic significance of EFNB2 and EphB4 genes in patients with oesophageal squamous cell carcinoma." in: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, Vol. 39, Issue 8, pp. 725-32, (2007) (PubMed).

Target Details for EPH Receptor B4

Target: EPH Receptor B4 (EPHB4)

Alternative Name: EPHB4

Background: EphB4: EPH receptor B4, also known as Htk, Myk1, Tyro11. Entrez Protein: NP_004435. It is a member of the Eph receptor family, which bind the ephrin ligand family. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The EphB4 protein binds to ephrin-B2 and plays an essential role in vascular development.

Molecular Weight: 108 kDa

UniProt: P54760

Pathways: RTK Signaling