EPO antibody

Catalog No. ABIN969109

This Mouse Monoclonal antibody specifically detects EPO in WB, ELISA and ICC. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for EPO antibody (ABIN969109)

Target: EPO (Erythropoietin (EPO))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPO antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 4F11

Product Details anti-EPO Antibody

Purpose: EPO Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human EPO expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-EPO antibody (ABIN969109)

Hirschler-Laszkiewicz, Tong, Conrad, Zhang, Flint, Barber, Barber, Cheung, Miller: "TRPC3 activation by erythropoietin is modulated by TRPC6." in: The Journal of biological chemistry, Vol. 284, Issue 7, pp. 4567-81, (2009) (PubMed).

Target Details for EPO

Target: EPO (Erythropoietin (EPO))

Alternative Name: EPO

Target Type: Hormone

Background: Human erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.Tissue specificity: Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.

Molecular Weight: 21 kDa

UniProt: P01588

Pathways: JAK-STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity