GATA1 antibody

Catalog No. ABIN969166

This Mouse Monoclonal antibody specifically detects GATA1 in WB, ELISA, IHC and ICC. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for GATA1 antibody (ABIN969166)

Target: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GATA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: 4F5

Product Details anti-GATA1 Antibody

Purpose: GATA1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human GATA1 expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-GATA1 antibody (ABIN969166)

Wierenga, Vellenga, Schuringa: "Down-regulation of GATA1 uncouples STAT5-induced erythroid differentiation from stem/progenitor cell proliferation." in: Blood, Vol. 115, Issue 22, pp. 4367-76, (2010) (PubMed).

Blackford, Parmigiani, Kensler, Wolfgang, Jones, Zhang, Parsons, Lin, Leary, Eshleman, Goggins, Jaffee, Iacobuzio-Donahue, Maitra, Klein, Cameron, Olino, Schulick, Winter, Vogelstein, Velculescu, Kinzler, Hruban: "Genetic mutations associated with cigarette smoking in pancreatic cancer." in: Cancer research, Vol. 69, Issue 8, pp. 3681-8, (2009) (PubMed).

Yerges, Klei, Cauley, Roeder, Kammerer, Moffett, Ensrud, Nestlerode, Marshall, Hoffman, Lewis, Lang, Barrett-Connor, Ferrell, Orwoll, Zmuda: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, (2009) (PubMed).

Target Details for GATA1

Target: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Alternative Name: GATA1

Background: Erythroid specific transcription factor,GATA sequence binding protein (same as EryF1,NF-E1,EF-1,EF gamma-a,GF1),expressed in RBC,mast cell,megakaryocyte,hematopoietic progenitor cell,testis,associated with a special class of nuclear bodies,activated by erythropoietin,inactivated by coactivation of DEATH receptors (TNFRSF6) mediated caspase cleavage Tissue specificity: Erythrocytes

Molecular Weight: 42.7 kDa

Gene ID: 2623

UniProt: P15976

Pathways: Cellular Response to Molecule of Bacterial Origin